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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dc485ab636136efa1adb0ff6f8f72e4eee9c2342b242f62e6a8f66f89aa0512' 
  AND token = 'HP96G1RrFlGD9fT/7G7kPk+mtUgFesGkzS9fdrVtdlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}