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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75496b8272c9df8448cb6cd7872544eb4b15d3caf4e66e833e03d60a4edab9d1' 
  AND token = '2LTvo/8+bALtHnQZ59YEOlE2+EeUI+fB9p1qIw9k6uY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}