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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '465b5ce543b67d0bd01ea9f489b4d99b20eb0ed0a97c1c5cf13fb753d5175c22' 
  AND token = 'hvxS1sCFZt83AX8bICCBKn222ixqTmxqaSZkT5HMiHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}