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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74478852d4e9b6e4e6141c7e672b968cfc5c4297d4bb8a5afa7e3163286278fa' 
  AND token = 'FNAi0kl5NDFgAQZw/plUXMbzzj7WHhj9mLNxP4xsXj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}