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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ef14e66cbb0983a0822bd5293210266cda86156429f8338719d9882126adda8' 
  AND token = 'sxXPLe5um7ciQ4QEGcg+OLvhunIdUsF+Hu5O4dPCvxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}