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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eade87892a28bf10d2c2e3e3a9f728edf255a09769b7d51bb5449fb7905e1b14' 
  AND token = 'OyGKUFyxiqn29iSJj/d6fQ8SNAyyPmI+KtVzpLXIyyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}