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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c1a4bf16e15b3a3fdf4561f47be830a3783c00f2a94999134214d30c4f62bbe' 
  AND token = 'McnPhLnk8eMxSZmn8isGDJnHXFcVsrwtBJMh2hBk6Mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}