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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5624ca1716b56c74b05cd69de2465ea44239d84a9d1dc364e4992672f24c12a' 
  AND token = '53w4ea1Kh3TC+7j7vVESItN72/fZ48JdDASbN8GYFso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}