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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0014c95ad65966fb2cac3213b64ad91e4225d697cf5da163095ad33cdf49dd5e' 
  AND token = 'mOGbrd7R1y+t8xDpo9dBNBXDnTI9fvDWz1gZcT9V6ms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}