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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8c6b4d2e706f811ecb374caba18721e86ae0a17c24ce6195da0472127b6d69d' 
  AND token = '9k46F8xfyUz9R0Rsa2NyEPkV1m4Nh0YjPGjM82dWoRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}