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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc8b6a1f16aafebfe8a039daf112f9e965fed8cf282206749b16c55cc677a61a' 
  AND token = 'I3CXtkZ1BeZTg1PJ0abiBqF4zuOeD5VqZ1+7krxo9hI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}