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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4be03f0b003110074c98ab1f2eb5707e99ec6b5d434536fe1853d23073b3f29' 
  AND token = 'ZEkPS2VOK3qzJek2UHdVuX+8gcuQ2Cru+3VFgXZA/u8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}