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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccca9335e5a7afb33a027f489c6786df54dc4c756b785edca0b09fee1c11a4b8' 
  AND token = 'QD+kkEAvFme8guSIqy0eu6qyQH2aUfUCNwcFqjEvFmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}