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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0d735fc055160c75c24b44b9d8345ba9a79a2291d9ee9ef3a479667ee48c8f8' 
  AND token = 'JqCjKIv1bPkYAWa9faRRPxGeYdn9odRpVtgD1KBz7SY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}