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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72866d964bd0ca041815327e5e298f245a7b8a3132804b3e9a7e0253331a3607' 
  AND token = 'rHrrRQuMkfk2Y3jymtptV5RF87oes1TXJri3Vv+o60I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}