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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '511498dc1f48be467cfde20cf94d2bec32a7bc3c604d7897145afaaa56a7b867' 
  AND token = 'bfMO72gurhJCbkeSEL+rSmhIfiAYCuPI5ZcR7nfA+nk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}