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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1209141b4e8348bb68ed166e66e38737938eb97e9c04d1539036d2aaa2611299' 
  AND token = 'djX37NO8XXua70DGtHAUAFp4ujS8TcsH1fcmpN8KBb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}