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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89906d114b69a7390d48d176898532cdab01b279c6168bbc5c81e8c83381df4f' 
  AND token = 'O1BqDXG8w49Zd2YeqBmfnhO+xAHEPh3OZllwlj9K8l8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}