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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0c4f94922f25214350c8f87e1383dc8bbdbc3eacb7292d99712aa06d4ee0455' 
  AND token = '9Ur2f6klcnfpXLaOVC/CFJZYI9+zxEZyvU5WamWPwbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}