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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fb7c35fe1e66e8723fc18d7d5e853caacf14ce022215648b83b938263b885ac' 
  AND token = 'FyJGI3Ph+MPR0SU+Q/ZcJc20zzxg+rR5bl9dPTLqGb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}