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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9216913bc10d2034d9eaa3ffa63828156d00fe34c80a2afab065b2acc354dcb3' 
  AND token = 'TWSsrCFznyD+5ODPQJ2t1aIILLAiV8uqbZFT77do1/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}