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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '114be3e7ca741e2968bb7a12a531740efe663002490b21b8df8c19b7ebab3301' 
  AND token = 'K7wRs2mFXH3Q+SavLKu16OMcPCWbx0Au+8BQRLPfirg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}