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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5de3be0b6654c2c1d24e3f8620b9b0d4994eca615db19e58bb792d800b7e545d' 
  AND token = 'oI+ypY24nRUbK0AlVb/mf/uu9Dzy5om0dMctShoJQrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}