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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16025de61d4a5e95562b4dfd8d731f854e738959602a080a2dfc23ab29eb2505' 
  AND token = 'EGFNx9KvGDFQHDe+I+0mIp1iRsQ76w0EoVVZwHSOL2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}