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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '716517350d8a064f8a1a4fe02425a53fdbb6464263e78ee255917df890ad2689' 
  AND token = 'k1VhYosplge2aSovxUBx25LBmaIpBx7mvHv9gihDPFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}