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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e491932f1f4025391a6ca92558d2063dbe187984ae874ddbec31946fc2d9f7c4' 
  AND token = 'hC1sxOVkMIv01SsMotlsxRZ915KkUtf36X0sT/HO86E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}