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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5c2ef30f80cff4c8d57858b9a04b3dd38f0c6318506082a830c243bc308d981' 
  AND token = 'BvRsTX7w6aGuoIp2S5XMTDujcnyj3AHb15Ibgq04578=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}