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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46f040dccf592cfea29195e76a0384fe13603a69e2d347a556584007013eb2b5' 
  AND token = 'OfPUyFsIJMcxAZIP/sAnDL/1SRt1BpMoCqPRKqDWc4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}