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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ac18322268edd5d33e53a4b953dd478990d05a52bff87bb2f2575d32dce2515' 
  AND token = '2D88wA9F1B+MiatTH9iasPPsk/YOm7mpk9RZAn9NlqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}