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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c72d07678cdb625c44e5a8db2b36f13f1b75af9c4ecfc640de83443ef8d9f72b' 
  AND token = 'LKume9qItXwiLyR3713de3rb7ntwPAapQS37LWd0Zp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}