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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c71093baf98c45fe0c27df0d9f3c8aecc8aa2045b8b3b739260220674061305' 
  AND token = 'IgvZDgqHUemkD3/LHwn7BTUOt9EDXD9Uh+K2e6r3kus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}