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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b957f3146cce00c9b782cbd77425422c6949992e5e38d8c099f46172904086bd' 
  AND token = 'nBY1ru+G4Ep6wMH4A7U+yQJ5BkfcT13qm9zuf6GlgQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}