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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ae8f73ad55fd73e06f06be4f780e39af6863516066b91a6859ef67ff67b3641' 
  AND token = 'nXlTkOhC1sh+c61wCaLNt/pTKH9Y/Jc7DEkOuvRIbuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}