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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e14ee0458a55bbe1d05ca02fe23d6ea2bebd45abdf7403c7450c77ee944e048' 
  AND token = 'CwVYikKiqDLtbyAskp1R1tTEiHL6/taqpFX9PvHnuPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}