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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e680948da44b869367bd47a8b3eed4195072155e4ca308f0614a20421cc62b1' 
  AND token = 'ISZxuMncChh2DfQ+RABpMtBAv9BRZeSSRq7oF5HyLiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}