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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9aad30e86a3cee9c54ab660a70fc438e6700c117d60004fcdc9535e155140401' 
  AND token = 'M5dFBlmPnlYNnkNS276ndXe8eyFf+5M/9vQPYZcH4w4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}