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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3280ff1faf49733c177fbda27923d72b1a8e902a35f92fc4fe00255b23106d0' 
  AND token = 'aTpW5HO9Arvpbaiz/94Cy3WGEABuzv19MMvA5oOxaKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}