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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '320cc353bfb4eb4e57645e0afe6edfb7e33dfda5d1d157b05ff5867a57d89cc3' 
  AND token = 'njUw36thqRaGY+edLbcAFz6ftnIDaSZ3I2gy4GzBSQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}