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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8e7d0204785f2363970f4d7248881d4a3e46d67bb14600331ca85e96382e215' 
  AND token = 'aPkmLjzOnjeZP6yqWe0xjoWCELz1BaF3VnbD7E1hNGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}