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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c75512a5fa121476f9d6541e1623a047a7785510b12fc1f03ff450b47d473803' 
  AND token = 'zspW2qrWS66NYeXPAi8AeXXZiUT7jzI/7CaqlNCCgmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}