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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85a6411a4a676ebf066ad93a30e0cc30453a2dcb16e683e1f8fac329eca2d6c2' 
  AND token = 'TMBrqV+bg7Gz1atI5SWVDiXXPbzMjgKAzol9HbxXqmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}