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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3291401a0fb93adbf15b0a57a738e50a28178849c9e0d89c15f6ea71884a835d' 
  AND token = 'Kya4OlxDU8DQZMK9tR7x3XAK4CYmmjAI3wP6BUS/SxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}