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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d1063a85f10218e7dddb5e8ef0dec60122d807ea29d77826a2439d74f5d9ccf' 
  AND token = '5EPJrVBOvWsodRuYM3+7teMDhePRGB+framenu+105E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}