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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a075465ebe0413805c532692e8666d5db3d26be135dafc6f5cfcc10950e294a7' 
  AND token = 'j1NEXwGkrro77I8eG9swqHmBa0dll3YmQ3q9Ldo/Z8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}