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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd25cc4a7a9e60cf0d544c3ba8f7fad95c5c60229221769230cee2c2b33c42f7b' 
  AND token = 'BAcPCxPBs4EG6D1DhJQXXZd+vVRAFWTF9fATnHYJQwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}