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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f1c3a2d8728bb34c4743de4bdd0f5dc23fdcd91cedb1b8bb95a914fa852c21a' 
  AND token = 'ELKwrfrx6pOaeoTHWtRclHalRqrKtxh/9YyDv+r8uX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}