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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16a05bd6e5ace36d2add226a816c4dd049152e531944eb7c766050b7fd08f581' 
  AND token = '+YK8KDEAG/gwz0Eyyr7H/ntWtk0ZDdlJlEyXJaHFjB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}