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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e375c0e45450aee172d7f11cff5e188c48e56b31a8de6f33b2d6b0ae5ad2ae3' 
  AND token = 'CaEv2NHIU3QBymUg+wt36zoHCwJDyeIoNj2iIh/LFlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}