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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50c882a137ac2b9902bd2a9d04a479b32ea45eeede8a61b82bfafbaeedbe2788' 
  AND token = 'mVQZkvi8b69z55/XaR4q8RcMQPpMFS5IaRnHWYNZEAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}