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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a6346dd33e3aedc9b2f1ec64e664810b84e71b6fff09d6a338c74f2e53bb359' 
  AND token = 'Ri+yJcOZtbYPrpwNruaoP06hNQWnwY4unddGr7UXsE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}